Symposium @ Society for Immunotherapy of Cancer (SITC) 2026 Annual Meeting

Friday, November 6, 2026  12:30pm - 1:30pm

Lunch Included

SYNC-T® Therapy SV-102: A Combination Drug/Device Immunotherapy Approach for Metastatic Prostate Cancer: Updated Long-Term Overall Survival

Join us to learn more about the updated SYNC-T Therapy SV-102 long-term overall survival data presented at ESMO 2026

West Building - 300 Level - 224B

Lunch included, seating is limited

Symposium Overview

Description of program and speakers

Title:  SYNC-T® Therapy SV-102: A Combination Drug/Device Immunotherapy Approach for Metastatic Prostate Cancer: Updated Long-Term Overall Survival

Speakers: Gerald Andriole, M.D. (Chief Medical Officer, Urology, Syncromune), Yousef Zakharia, M.D. (Chair, Genitourinary Malignancy Disease Group, Mayo Clinic Arizona), and Akash Patnaik, M.D., Ph.D., MMSc (Associate Professor of Medicine, University of Chicago)

Description: Leading investigators and clinical innovators will provide in-depth insights into SYNC-T SV-102, a novel combination intratumoral/locoregional immunotherapy designed to elicit a systemic antitumor response in patients with metastatic castration-resistant prostate cancer (mCRPC).

This session will showcase Phase 1 clinical results demonstrating safety, immune activation, and early signs of efficacy, and highlighting new long-term overall survival data recently presented at ESMO 2026.

The symposium will also spotlight the LEGION-100 Phase 2 clinical trial, now actively enrolling patients and recruiting clinical trial sites across the U.S. Investigators will share insights into the trial’s design, scientific rationale, and the opportunity for institutions to partner in evaluating this cutting-edge immunotherapy.

Key Topics

Immunotherapy in mCRPC

Trials and data to date.

Novel in situ SYNC-T Therapy

Combination intratumoral / locoregional

Phase 1 Long-Term OS Data

Phase 1 data in mCRPC

LEGION-100 Phase 2 Trial for mCRPC

Trial design, rationale, participation.

Speakers

The symposium will feature three speakers who have broad expertise on the SYNC-T Therapy

Gerald Andriole, M.D.

Chief Medical Officer, Urology,  Syncromune, Inc.

Yousef Zakharia, M.D.

Chair, Genitourinary Malignancy Disease Group, Mayo Clinic Arizona

Akash Patnaik, M.D., Ph.D., MMSc

Associate Professor of Medicine, University of Chicago

Program Details

12:30pm – 1:30pm

12:30pm - 12:45pm

Picture of Gerald Andriole, M.D.

Gerald Andriole, M.D.

  • Previous immunotherapy trials for mCRPC and discussion of outcomes

  • Introduction to SYNC-T, a novel third-generation combination intratumoral/locoregional immunotherapy

  • Potential advantages of SYNC-T Therapy in treating mCRPC

12:45pm - 1:05pm

Picture of Yousef Zakharia, M.D.

Yousef Zakharia, M.D.

  • Overview of Phase 1 trial of SYNC-T Therapy SV-102 in mCRPC

  • Outcomes: safety, efficacy, pharmacokinetics

  • Updated Long-Term OS Data

1:05pm - 1:20pm

Picture of Akash Patnaik, MD, PhD, MMSc

Akash Patnaik, MD, PhD, MMSc

  • LEGION-100 Phase 2 Dose Escalation and Dose Optimization Trial design

  • Key inclusion and exclusion criteria

  • How to refer patients or become a clinical trial site

1:20pm - 1:30pm

  • Question and Answer Session

Conference Directions

West Building, 300 Level – 224B

Society for Immunotherapy of Cancer (SITC) 2026 Annual Meeting
Phoenix Convention Center
100 N. 3rd St.
Phoenix, AZ 85004
602-262-6225
West Building – 300 Level – 224B

About Syncromune

Pioneers in Combination Multi-Target Intratumoral Immunotherapy

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